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| 24-Sep-21 19:00
Estadio Eva Perón
Ref:Rapallini
Lm 1:Núñez, I
Lm 2:Castelli, JM
|
 | Sarmiento de Junín
| 0 - 1 | Velez Sarsfield
73' Lucero, JM (1991)
|
| |
| 24-Sep-21 21:15
Jorge Luis Hirschi
Ref:Abal
Lm 1:Carretero
Lm 2:Delbarba
|
 | Estudiantes de La Plata
Del Prete, G 20'
| 1 - 1 | Platense
70' Tissera
|
| |
| 25-Sep-21 13:30
Jose Maria Minella
Ref:Echavarría
Lm 1:Romero
Lm 2:Vallejos
|
 | Aldosivi
Grahl, F 62'
| 1 - 3 | Gimnasia y Esgrima de La Plata
1' Rodríguez, Luis (1985)
24' Contín
55' Contín
|
| |
| 25-Sep-21 15:45
Estadio Mario Alberto Kempes
Ref:Pitana
Lm 1:González, P
Lm 2:Uziga
|
 | Talleres de Cordoba
Tenaglia, N 18'
Retegui 40'
Retegui 45'
Valoyes, DL 68'
| 4 - 1 | Rosario Central
45' Marinelli, A
|
| |
| 25-Sep-21 15:45
Julio H. Grondona
Ref:Rey Hilfer
Lm 1:Rosetti
Lm 2:Vázquez, JM
|
 | Arsenal Sarandi
Sepúlveda, B 48'
| 1 - 0 | Lanus
|
| |
| 25-Sep-21 18:00
Florencio Sola
Ref:Trucco
Lm 1:Savorani
Lm 2:Gualtieri
|
 | Banfield
Cruz, JM 10'
Cruz, JM 26'
| 2 - 0 | Atletico Tucumán
|
| |
| 25-Sep-21 20:15
Estadio Alfredo Terrera
Ref:Penel
Lm 1:Germanotta
Lm 2:Bistocco
|
 | Central Cordoba Sgo del Estero
Sequeira, Leo 71' 
| 1 - 3 | River Plate
32' Carrascal, J
62' Álvarez, Julián
86' Romero, Braian
|
| |
| 26-Sep-21 13:30
15 de Abril
Ref:Merlos
Lm 1:Martín
Lm 2:Espinoza
|
 | Union Santa Fe
Luna, Mauro 47'
Luna, Mauro 68'
| 2 - 0 | Patronato de Parana
|
| |
| 26-Sep-21 15:45
Nuevo Gasometro
Ref:Espinoza, F
Lm 1:Navarro
Lm 2:Verlotta
|
 | San Lorenzo
Fernández, Nicolás (2000jan) 23'
Rosane 45'
| 2 - 1 | Defensa y Justicia
57' Pizzini
|
| |
| 26-Sep-21 18:00
Libertadores de America
Ref:Herrera
Lm 1:Rodríguez, F
Lm 2:Raineri
|
 | Independiente
Márquez, Rodrigo 60'
| 1 - 4 | Godoy Cruz Mendoza
 og 24' Ortega, T
45' Badaloni
50' Bullaude
63' Ojeda, Martín (1998)
|
| |
| 26-Sep-21 20:15
Bombonera
Ref:Lamolina, N
Lm 1:Scime
Lm 2:Castelli, M
|
 | Boca Juniors
Orsini 66'
| 1 - 0 | Colón de Santa Fe
|
| |
| 27-Sep-21 18:00
Diego Armando Maradona
Ref:Pérez, Yael
Lm 1:Maidana
Lm 2:Lencina, Gerardo
|
 | Argentinos Juniors
Cabrera, Javier 3'
Mac Allister, K 13'
| 2 - 0 | Racing Club
|
| |
| 27-Sep-21 20:15
Estadio Marcelo Bielsa
Ref:Echenique
Lm 1:Fernández, J
Lm 2:Acevedo
|
 | Newells Old Boys
| 0 - 1 | Huracán
24' Cóccaro, M
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