| Lineups found Starting lineup changes since last game |
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| July 2022 |
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| Coach Terzić since 23-May-22 |
| M.1 | 29-Jul | away | TSV 1860 | | 0-3 | 4-2-3-1 | |
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| August 2022 |
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 05-Aug to 12-Nov Haller, S Illness |
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| 05-Aug to 07-Aug Passlack Hip Injury |
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| 05-Aug to 07-Aug Rothe, T Hip Injury |
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| 05-Aug to 21-Aug Süle Muscle Injury |
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| 11-Aug to 11-Sep Adeyemi, K Foot Injury |
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| 11-Aug to 21-Aug Reyna, G Injury |
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| 26-Aug to 11-Sep Malen Thigh Injury |
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| 26-Aug to 12-Nov Dahoud Shoulder Injury |
| October 2022 |
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| 05-Sep to 12-Nov Bynoe-Gittens Shoulder Injury |
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| 09-Sep to 04-Oct Kobel Muscle Injury |
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| 09-Sep to 11-Sep Hazard, T Thigh Injury |
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| 30-Sep to 12-Nov Reus Ankle Injury |
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| 30-Sep to 06-Oct Reyna, G Muscle Injury |
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| 04-Oct to 06-Oct Hummels Illness |
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| 04-Oct to 06-Oct Wolf, M Injury |
| M.2 | 19-Oct | away | Hannover | | 0-2 | 4-2-3-1 | In:Can, Özcan, Hazard, Brandt, Out:Belling., Dahoud, Adeyemi, Reus, |
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| January 2023 |
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| Coach Reutershahn since 01-Jan-23 |
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| 21-Oct to 12-Nov Meunier Injury |
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 24-Oct to 26-Oct Özcan, S Yellow Cards |
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| 24-Oct to 03-Nov Raphaël Guerreiro Injury |
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| 01-Nov to 12-Nov Rothe, T Knee Injury |
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| 01-Nov to 12-Nov Wolf, M Rest |
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| 21-Jan to 19-Mar Kamara, Abdoulaye Knee Injury |
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| 21-Jan to 10-Feb Meunier Thigh Injury |
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| 21-Jan to 23-Jan Can Muscle Injury |
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| 21-Jan to 26-Jan Reus Illness |
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| 24-Jan to 26-Jan Bellingham Yellow Cards |
| February 2023 |
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| 03-Feb to 05-Feb Özcan, S Yellow Cards |
| M.3 | 08-Feb | away | Bochum | | 1-2 | 4-1-4-1 | In:Wolf, M, Hummels, Ryerson, Belling., B-Gitte., Haller, Out:Meunier, Schlott., R Guerreiro, Hazard, Malen, Moukoko, |
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| April 2023 |
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| 10-Feb to 12-Feb Adeyemi, K Yellow Cards |
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| 10-Feb to 12-Feb Rothe, T Knock |
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| 10-Feb to 18-Feb Wolf, M Shoulder Injury |
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| 14-Feb to 31-Mar Moukoko, Y Ankle Injury |
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| 18-Feb to 18-Mar Hazard, T Muscle Injury |
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| 24-Feb to 31-Mar Adeyemi, K Thigh Injury |
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| 06-Mar to 08-Mar Ryerson Yellow Cards |
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| 10-Mar to 19-Mar Brandt, Julian Muscle Injury |
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| 10-Mar to 12-Mar Reus Illness |
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| 17-Mar to 19-Mar Can Yellow Cards |
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| 17-Mar to 19-Mar Kobel Hip Injury |
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| 31-Mar to 07-Apr Meunier Back Injury |
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| 31-Mar to 14-Apr Reyna, G Illness |
| M.4 | 05-Apr | away | Leipzig | | 2-0 | 4-2-3-1 | In:Reus, R Guerreiro, Malen, Out:Belling., B-Gitte., Haller, |
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| May 2023 |
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| 07-Apr to 07-May Schlotterbeck, N Thigh Injury |
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| 14-Apr to 21-Apr Süle Thigh Injury |
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| 21-Apr to 28-May Meunier Muscle Injury |
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| 27-Apr to 14-May Coulibaly, Soumaïla Knee Injury |
| June 2023 |
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| 12-May to 28-May Bynoe-Gittens Shoulder Injury |
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| 20-May to 26-May Bellingham Knee Injury |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |