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Once Caldas Substitutions at Apertura 2021
| Most In | | Most Out | | Otálvaro | 6 times | 25 minutes avg | | Estacio, A | 5 | 14 | | Burbano, F | 5 | 24 | | Mejia, Robert | 4 | 39 | | García, Alejandro (2001) | 4 | 21 | | Guzmán, SF | 4 | 13 | | Laszo | 4 | 36 | | Quiñonez, Dannovi | 3 | 6 | | Cubides | 3 | 5 | | Romero, Antonio (1997) | 3 | 18 | | García, Mender | 3 | 28 | | Hernández, Sebastián (1986) | 3 | 14 | | Valoyes, P | 2 | 22 | | Carreazo | 2 | 36 | | Beltrán, Esteban | 1 | 14 | | Balanta, D | 1 | 38 |
| | | Hernández, Sebastián (1986) | 7 times | 68 minutes avg | | Mejia, Robert | 7 | 74 | | Otálvaro | 7 | 69 | | Carreazo | 6 | 71 | | García, Alejandro (2001) | 6 | 71 | | Burbano, F | 5 | 66 | | Guzmán, SF | 3 | 64 | | Lemos, DF | 3 | 80 | | Quiñonez, Dannovi | 2 | 59 | | Estacio, A | 1 | 46 | | Clavijo, JT | 1 | 46 | | Laszo | 1 | 74 | | García, Mender | 1 | 60 | | González, Yoiver | 1 | 52 | | Romero, Antonio (1997) | 1 | 73 | | Valoyes, P | 1 | 46 |
| | 18 games found - Color References: GK, DF, DM, MF, FW , Unknown Pos |
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