| Lineups found Starting lineup changes since last game |
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| September 2012 |
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| Coach Emery since 11-Jun-12 |
| M.1 | 19-Sep | away | Barcelona | | 3-2 | 4-5-1 | |
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| October 2012 |
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 23-Sep to 20-Mar Rômulo, Borges anterior cruciate ligament knee injury |
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 28-Sep to 01-Oct McGeady 4th yellow card ban |
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| 29-Sep to 15-Nov Dikan Shoulder |
| M.2 | 02-Oct | | Celtic | | 2-3 | 4-2-3-1 | In:Pesyakov, Makeev, Pareja, d Zeeuw, Out:Dikan, Kombarov, Suchý, Rômulo, |
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| 04-Oct to 08-Oct Makeev 4th yellow card ban |
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| 16-Oct to 26-Nov McGeady Unknown injury |
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| 16-Oct to 25-Oct Yakovlev Knee |
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| 17-Oct to 25-Oct Emenike Back |
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| 20-Oct to 30-Nov Pesyakov Footstep fracture |
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| 22-Oct to 24-Oct Insaurralde, JM Champions League red card ban (1 match) |
| M.3 | 23-Oct | | Benfica | | 2-1 | 4-2-3-1 | In:Rebrov, Suchý, Bilyale., Jurado, Ananidze, Out:Pesyakov, Insaurr., d Zeeuw, McGeady, Emenike, |
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| November 2012 |
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| 26-Oct to 28-Oct Kombarov, K Red card ban |
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| 26-Oct to 29-Oct Welliton 4th yellow card ban |
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| 01-Nov to 20-Nov Welliton Unknown injury |
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| 03-Nov to 13-Nov Emenike Unknown injury |
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| 07-Nov to 07-Feb Bilyaletdinov Groin |
| M.4 | 07-Nov | away | Benfica | | 2-0 | 4-2-3-1 | In:Kombarov, Insaurr., Out:Suchý, Ananidze, |
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| 08-Nov to 12-Nov Rafael Carioca 4th yellow card ban |
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| 09-Nov to 16-Nov Ananidze Family reasons |
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| 17-Nov to 30-Nov Rebrov, A Unknown injury |
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| 19-Nov to 21-Nov Pareja Champions League red card ban (1 match) |
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| 20-Nov to 31-Dec Welliton Unknown injury |
| M.5 | 20-Nov | | Barcelona | | 0-3 | 4-2-3-1 | In:Dikan, Suchý, Emenike, Out:Rebrov, Pareja, Bilyale., |
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| December 2012 |
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| Coach Karpin since 26-Nov-12 |
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| 29-Nov to 04-Dec Ari 4th yellow card ban |
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| 30-Nov to 31-Dec Ananidze Meniscus |
| M.6 | 05-Dec | away | Celtic | | 2-1 | 4-2-3-1 | In:Pesyakov, Dzyuba, Out:Dikan, Makeev, |
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| February 2013 |
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| 07-Dec to 11-Dec Pareja Red card ban |
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| 07-Dec to 11-Dec Insaurralde, JM Red card and foul play ban - 1st match of 3 |
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| 07-Dec to 11-Dec Emenike 4th yellow card ban |
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| 10-Dec to 10-Jan Makeev Knee |
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| 06-Feb to 23-Apr Emenike Unknown injury |
| March 2013 |
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| 28-Feb to 08-Mar Pareja Unknown injury |
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| 08-Mar to 12-Mar Insaurralde, JM Red card and foul play ban - 2nd match of 3 |
| April 2013 |
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| 15-Mar to 17-Mar Insaurralde, JM Red card and foul play ban - 3rd match of 3 |
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| 16-Mar to 16-Apr Bilyaletdinov Unknown injury |
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| 22-Mar to 05-May Ananidze Unknown injury |
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| 31-Mar to 10-Apr Dzyuba Knee ligaments |
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| 26-Apr to 29-Apr Suchý 8th yellow card ban |
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| 26-Apr to 29-Apr Rafael Carioca Red card ban |
| May 2013 |
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| 09-May to 12-May McGeady Red card, violent and insulting conduct ban - 1st match of 6 |
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| 17-May to 20-May McGeady Red card, violent and insulting conduct ban - 2nd match of 6 |
| Color References: GK, DF, DM, MF, FW , Unknown Pos |